T.D. Anyaegbunam was a significant figure in 19th- and early 20th-century Nigeria, widely recognized for his work as a translator of the Bible into the Igbo language and for his role in establishing early educational institutions.
He was part of the core Bible translation team, alongside figures such as Thomas John Dennis and C.D. Green, responsible for translating the Bible into a standardized Union Igbo dialect. He also co-authored The Epistle of Paul the Apostle to the Romans in the Ibo Language with Henry Hughes Dobinson.
Closely associated with the Church Missionary Society (CMS), T.D. Anyaegbunam contributed to education by establishing a night school in Onitsha in 1893.
An Onitsha-born catechist, he worked closely with missionaries such as Thomas Dennis, supporting the establishment of new mission stations, including the station at Egbu near Owerri. This location was selected as the headquarters for Igbo language studies due to the purity of the local dialect.
He is recognized for his contributions to religious development and education in the region during the colonial era.